reporter probe

synonym: signalling probe
https://doi.org/10.1351/goldbook.09880

Specifically designed single-stranded deoxyribonucleic acid (ssDNA) (alternatively, ribonucleic acid (RNA) or a synthetic nucleic acid analogue such as locked nucleic acid (LNA) or peptide nucleic acid (PNA)) with a defined (known) nucleotide sequence used to detect complementary DNA or RNA sequence in a sample.

Notes:
  1. Reporter probe is usually labelled (radioactively, immunologically, or by fluorescent, electroactive, or other species to produce a specific signal upon hybridization).
  2. Similar to capture probes, nucleic acid signalling probes (or nucleic acid aptamers) can be applied in studies of nucleic acid interactions with proteins and other ligands.
Source:
PAC, 2018, 90, 1121. (Terminology of bioanalytical methods (IUPAC Recommendations 2018)) on page 1186 [Terms] [Paper]
Citation: 'reporter probe' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.09880 RIS BibTex EndNote
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