nucleic acid aptamers

mentioned: systematic evolution of ligands by exponential enrichment (SELEX)
https://doi.org/10.1351/goldbook.09709
Single stranded (ss) oligonucleotides (mainly deoxyribonucleic acid (DNA) or ribonucleic acid (RNA)) originating from in vitro selection, which, starting from random sequence libraries, optimise the nucleic acids for high-affinity binding to a given target.
Note: In vitro selection is an iterative method mainly known as Systematic Evolution of Ligands by EXponential enrichment (SELEX).
Source:
PAC, 2018, 90, 1121. (Terminology of bioanalytical methods (IUPAC Recommendations 2018)) on page 1148 [Terms] [Paper]
Citation: 'nucleic acid aptamers' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.09709 RIS BibTex EndNote
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