https://doi.org/10.1351/goldbook.08306
Three-dimensional nuclear magnetic resonance spectroscopy for the assignment of protein structure with one carbon and two hydrogen dimensions.
Notes:
- In the initial HMQC step, magnetization is transferred from \(\ce{^{1}H}\) to \(\ce{^{13}C}\) and back again. This is then followed by a NOESY step in which the magnetization is transferred to any other hydrogen nucleus close by before detection.
- The technique requires \(\ce{^{13}C}\) labelling.
- The spectrum is used to obtain restraints for structure calculations.