linearised multistage model

https://doi.org/10.1351/goldbook.15859
Sequence of steps in which (a) a multistage model is fitted to tumor incidence data; (b) the maximum linear term consistent with the data is calculated; (c) the low-dose slope of the dose–response function is equated to the coefficient of the maximum linear term; and (d) the resulting slope is then equated to the upper bound of potency.
Source:
PAC, 2007, 79, 1153. (Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)) on page 1251 [Terms] [Paper]
Citation: 'linearised multistage model' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.15859 RIS BibTex EndNote
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