nucleotide-binding oligomerization domain-containing protein 1, 2

initialisms: NOD1, NOD2
https://doi.org/10.1351/goldbook.13519
Members of a family of human intracellular proteins involved in the detection of invasive bacteria and activation of the $\ce{NF\kappa B}$ transcription factor pathway.
Note: In epithelial cells, NOD1 is essential for sensing intracellular Gram-negative bacteria through a tripeptide motif in the bacterial peptidoglycan.
Source:
PAC, 2012, 84, 1113. (IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)) on page 1222 [Terms] [Paper]
Citation: 'nucleotide-binding oligomerization domain-containing protein 1, 2' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.13519 RIS BibTex EndNote
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