two-generation reprotox study

https://doi.org/10.1351/goldbook.11334

Procedure in rodents wherein parents (P0 generation) and their offspring (F1 generation) are both exposed to a test substance and the second generation (F2) is examined for possible toxic effects.

Source:
PAC, 2016, 88, 713. (Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)) on page 816 [Terms] [Paper]