congenital adrenal hyperplasia

synonym: adrenogenital syndrome
https://doi.org/10.1351/goldbook.10553

Group of disorders caused by hyperplasia of the adrenal cortex or by malignant tumors, resulting in excess secretion of adrenocortical androgenic hormones, and characterized by masculinization of women, feminization of men, or precocious puberty in the male.

Note: The condition is associated with a decrease in the blood level of cortisol and an increase in the level of androgens in both sexes, most commonly as a result of 21-hydroxylase deficiency.
Source:
PAC, 2016, 88, 713. (Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)) on page 739 [Terms] [Paper]