capture probe

https://doi.org/10.1351/goldbook.09865

Specifically-designed single-stranded nucleic acid with a defined (known) nucleotide sequence immobilised on a surface.

Notes:
  1. Capture probes are utilised as a recognition element to test the nucleotide sequence of target deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) in the sample solution by using DNA or RNA hybridization.
  2. An analogous principle, based on immobilised nucleic acid probes, has been applied in studies of the interactions of nucleic acids with proteins or other targets. See also nucleic acid aptamers.
Examples: Nucleic acids: ssDNA (alternatively, RNA or a synthetic nucleic acid analogue, such as locked nucleic acid (LNA) or peptide nucleic acid (PNA)). Surfaces: microarray, magnetic, or other micro/nanoparticle, a transducer of a biosensor.
Source:
PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1183 (https://doi.org/10.1515/pac-2016-1120)