https://doi.org/10.1351/goldbook.P04578
Technique by which a photochemically reactive molecular entity, specifically associated with a biomolecule, is photo-excited in order to covalently attach a @L03424@ to the biomolecule, usually via intermediates. Identification of the resulting photo-crosslinked product provides structural information on the protein′s @B00649@.
Notes:
- Technique widely used for identifying in general ligand-@RT06841@ interactions in biological macromolecules and in particular the @B00649@ within @P04898@.
- Typical examples are @N04145@, @C00806@, ketone excited states, cations and radicals.