mechanism-based inhibition

Synonym: suicide inhibition
https://doi.org/10.1351/goldbook.M03805
Irreversible @I03034@ of an enzyme due to its @C00874@ of the reaction of an artificial substrate. Also called 'suicide inhibition'.
Source:
PAC, 1994, 66, 1077. (Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)) on page 1138 [Terms] [Paper]
Citation: 'mechanism-based inhibition' in IUPAC Compendium of Chemical Terminology, 3rd ed. International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. https://doi.org/10.1351/goldbook.M03805 RIS BibTex EndNote
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Last revised: February 24, 2014