Title: enzymes Long Title: IUPAC Gold Book - enzymes DOI: 10.1351/goldbook.E02159 Status: current Definition Macromolecules, mostly of protein nature, that function as (bio)catalysts by increasing the reaction rates. In general, an enzyme catalyses only one reaction type (reaction specificity) and operates on only one type of substrate (substrate specificity). Substrate molecules are attacked at the same site (regiospecificity) and only one or preferentially one of the enantiomers of chiral substrates or of racemic mixtures is attacked (stereospecificity). Related Terms - (bio)catalysts: https://goldbook.iupac.org//terms/view/B00652 - chiral: https://goldbook.iupac.org//terms/view/C01057 - racemic: https://goldbook.iupac.org//terms/view/R05026 - substrate: https://goldbook.iupac.org//terms/view/S06083 Sources - PAC, 1992, 64, 143. 'Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)' on page 152 (https://doi.org/10.1351/pac199264010143) - PAC, 1993, 65, 2291. 'Nomenclature of kinetic methods of analysis (IUPAC Recommendations 1993)' on page 2295 (https://doi.org/10.1351/pac199365102291) - PAC, 1994, 66, 2587. 'Glossary of bioanalytical nomenclature - Part 1: General terminology, body fluids, enzymology, immunology (IUPAC Recommendations 1994)' on page 2593 (https://doi.org/10.1351/pac199466122587) Other Outputs - html: https://goldbook.iupac.org/terms/view/E02159/html - json: https://goldbook.iupac.org/terms/view/E02159/json - xml: https://goldbook.iupac.org/terms/view/E02159/xml Citation: Citation: 'enzymes' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.E02159 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. Accessed: 2026-05-01T07:04:27+00:00