https://doi.org/10.1351/goldbook.D01685
Constitutionally equivalent atoms or groups of a molecule which are not symmetry related. Replacement of one of two diastereotopic atoms or groups results in the formation of one of a pair of @D01679@. In the example below the two hydrogen atoms of the @M03881@ group C-3 are diastereotopic.
D01685.png
See also:
prochirality
,
enantiotopic
,
heterotopic
Source:
PAC, 1996, 68, 2193. (Basic terminology of stereochemistry (IUPAC Recommendations 1996)) on page 2206 [Terms] [Paper]