Title: clearance Long Title: IUPAC Gold Book - clearance DOI: 10.1351/goldbook.CT01101 Status: current Index: quantity Definition Product of the concentration of a component in an output system and the volume flow rate of that output system divided by the concentration of this component in the input system. Note The term mean volume rate is recommended for this quantity. Related Terms - clearance: https://goldbook.iupac.org//terms/view/CT06860 - mean volume rate: https://goldbook.iupac.org//terms/view/M03787 - volume flow rate: https://goldbook.iupac.org//terms/view/V06642 Source - PAC, 1996, 68, 957. 'Glossary of terms in quantities and units in Clinical Chemistry (IUPAC-IFCC Recommendations 1996)' on page 966 (https://doi.org/10.1351/pac199668040957) Other Outputs - html: https://goldbook.iupac.org/terms/view/CT01101/html - json: https://goldbook.iupac.org/terms/view/CT01101/json - xml: https://goldbook.iupac.org/terms/view/CT01101/xml Citation: Citation: 'clearance' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.CT01101 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. Accessed: 2026-04-18T22:59:24+00:00