toxicity equivalency factor

symbol: $f$
initialism: TEF
https://doi.org/10.1351/goldbook.15103
  1. Ratio of the toxicity of a chemical to that of another structurally related chemical (or index compound) chosen as a reference.
  2. In risk assessment, ratio of the toxicity of a chemical to that of another structurally related chemical (or index compound) chosen as a reference. Factor used to estimate the toxicity of a complex mixture, commonly a mixture of chlorinated dibenzo-p-dioxins [oxanthrenes], furans, and biphenyls: in this case, TEF is based on relative toxicity to 2,3,7,8-tetrachlorodibenzo-p-dioxin [2,3,7,8-tetrachlorooxanthrene] for which the \(f = 1\).
Source:
PAC, 2009, 81, 829. (Glossary of terms used in ecotoxicology (IUPAC Recommendations 2009)) on page 957 [Terms] [Paper]
Citation: 'toxicity equivalency factor' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.15103 RIS BibTex EndNote
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