https://doi.org/10.1351/goldbook.14832
Geometric mean of the lowest exposure concentration that causes a statistically significant adverse effect (lowest-observed-effect concentration, LOEC) and the highest exposure concentration where no effect is observed (no-observed-effect concentration, NOEC) in a life-cycle (full chronic) or partial lifecycle (partial chronic) test.
Note: Calculation of an MATC requires quantitative life-cycle toxicity data on the effects of a material on survival, growth, and reproduction.