screen validation

https://doi.org/10.1351/goldbook.14190
Assay conditions, as determined by assay validation, are performed in the chosen plate format with an acceptable signal to background ratio as described by the Z′ factor.
Note: Validation typically requires testing a number of samples a minimum of three times and allows for the estimation of false positives, false negatives, and the selection of statistically significant thresholds.
Source:
PAC, 2011, 83, 1129. (Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)) on page 1154 [Terms] [Paper]
Citation: 'screen validation' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.14190 RIS BibTex EndNote
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