negative assay control

synonym: low control
https://doi.org/10.1351/goldbook.14168
Experimental conditions designed to produce the signal reflective of the absence of the process under investigation.
Note: For a binding or an activation mechanism, it is typically the signal measured in the absence of a test compound and is often relevant to the determination of the background signal. For an inhibitory or antagonist mechanism, it is the maximal signal, obtained in the absence of the reference inhibitor.
Source:
PAC, 2011, 83, 1129. (Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)) on page 1149 [Terms] [Paper]
Citation: 'negative assay control' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.14168 RIS BibTex EndNote
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