Monro–Kellie hypothesis

synonyms: Monro doctrine, Monro–Kellie doctrine
https://doi.org/10.1351/goldbook.11881
Hypothesis that the intracranial volume is unchangeable and therefore a constant intracranial pressure requires that the sum of the volumes of the three compartments blood, brain tissue and cerebrospinal fluid remains constant.
Source:
PAC, 2015, 87, 841. (IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)) on page 882 [Terms] [Paper]
Citation: 'Monro–Kellie hypothesis' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.11881 RIS BibTex EndNote
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