https://doi.org/10.1351/goldbook.10960
- Test for mutagenicity in which animals are treated with a test agent, after which time the frequency of micronucleated cells is determined.
Note: If a test group shows significantly increased levels of micronucleated cells compared to a control group, the chemical is considered capable of inducing chromosomal damage. - Procedure to detect clastogenic or aneugenic agents by microscopic examination of chromosomes.
Note: The test can be performed in vivo in rodents, or in cell culture (in vitro mammalian cell micronucleus test).