micronucleus test

https://doi.org/10.1351/goldbook.10960
  1. Test for mutagenicity in which animals are treated with a test agent, after which time the frequency of micronucleated cells is determined.
    Note: If a test group shows significantly increased levels of micronucleated cells compared to a control group, the chemical is considered capable of inducing chromosomal damage.
  2. Procedure to detect clastogenic or aneugenic agents by microscopic examination of chromosomes.
    Note: The test can be performed in vivo in rodents, or in cell culture (in vitro mammalian cell micronucleus test).
Source:
PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 779 (https://doi.org/10.1515/pac-2015-1202)