in vitro estrogen activity assay

https://doi.org/10.1351/goldbook.10681
  1. Procedure in which a tumor cell line is exposed to a test substance and activation of the estrogen receptor is studied by a reporter molecule in order to assess the estrogen-sensitivity of the tumor.
  2. Test using estrogen-sensitive cells to evaluate estrogenic activity of a substance or environmental sample.
Compare: uterotrophic assay
Source:
PAC, 2016, 88, 713. (Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)) on page 751 [Terms] [Paper]
Citation: 'in vitro estrogen activity assay' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.10681 RIS BibTex EndNote
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