10681 IUPAC Gold Book - in vitro estrogen activity assay 10.1351/goldbook.10681 10681 current 1 Procedure in which a tumor cell line is exposed to a test substance and activation of the estrogen receptor is studied by a reporter molecule in order to assess the estrogen-sensitivity of the tumor. Test using estrogen-sensitive cells to evaluate estrogenic activity of a substance or environmental sample. estrogen https://goldbook.iupac.org//terms/view/10680 tumor https://goldbook.iupac.org//terms/view/11330 uterotrophic assay https://goldbook.iupac.org//terms/view/11349 PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 751 (https://doi.org/10.1515/pac-2015-1202) https://goldbook.iupac.org/terms/view/10681/html https://goldbook.iupac.org/terms/view/10681/json https://goldbook.iupac.org/terms/view/10681/plain Citation: 'in vitro estrogen activity assay' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10681 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-05-28T06:37:32+00:00