hold-up time

in chromatography
symbol: $t_{\rm{M}}$
https://doi.org/10.1351/goldbook.10038
Time required to elute a component which is not retained by the stationary phase.
Notes:
  1. The hold-up time includes any time that the component spends in the sample injector, the detector, and connectors.
  2. The hold-up time is related to the hold-up volume (\(V_{\rm{M}}\)) and flow rate (\(F_{\rm{c}}\)) by \(t_{\rm{M}} = V_{\rm{M}}⁄F_{\rm{c}}\) .
Source:
PAC, 2017, 90, 181. (Terminology of separation methods (IUPAC Recommendations 2017)) on page 196 [Terms] [Paper]
Citation: 'hold-up time' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.10038 RIS BibTex EndNote
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