peptide de novo sequencing

https://doi.org/10.1351/goldbook.09757
Analytical process that derives an amino acid sequence of a peptide from its tandem mass spectrum without the assistance of a sequence database.
Note: It is defined in contrast to protein/peptide identification using a database search. An advantage of de novo sequencing is its applicability to both known and novel peptides from organisms with unsequenced genome.
Source:
PAC, 2018, 90, 1121. (Terminology of bioanalytical methods (IUPAC Recommendations 2018)) on page 1158 [Terms] [Paper]
Citation: 'peptide de novo sequencing' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.09757 RIS BibTex EndNote
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