electron-transfer/higher-energy collision dissociation

in proteomics
initialism: EthcD
mentioned: post-translational modification (PTM)
https://doi.org/10.1351/goldbook.09743

Ion fragmentation technique in mass spectrometry-driven proteomics that is a combination of electron-transfer dissociation (ETD) and higher-energy collision dissociation (HCD) in Kingdon trap instruments (Orbitrap™).

Note: The dual fragmentation allows generation of rich MS/MS spectra for peptide sequencing and post-translational modification (PTM) analysis.
Source:
PAC, 2018, 90, 1121. (Terminology of bioanalytical methods (IUPAC Recommendations 2018)) on page 1155 [Terms] [Paper]
Citation: 'electron-transfer/higher-energy collision dissociation' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.09743 RIS BibTex EndNote
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