single nucleotide polymorphism

synonym: point mutation
initialism: SNP
https://doi.org/10.1351/goldbook.09727

Variant of nucleotide sequence of deoxyribonucleic acid (DNA) in which the purine or pyrimidine base of a single nucleotide is replaced by another such base.

Notes:
  1. SNP is the most common type of change in DNA.
  2. SNPs occur normally throughout a human DNA once in every 300 nucleotides on average, which means there are roughly 10 million SNPs in any typical human genome. They can act as biological (diagnostic) markers.
Source:
PAC, 2018, 90, 1121. (Terminology of bioanalytical methods (IUPAC Recommendations 2018)) on page 1153 [Terms] [Paper]
Citation: 'single nucleotide polymorphism' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.09727 RIS BibTex EndNote
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