Variant of nucleotide sequence of deoxyribonucleic acid (DNA) in which the purine or pyrimidine base of a single nucleotide is replaced by another such base.
Notes: - SNP is the most common type of change in DNA.
- SNPs occur normally throughout a human DNA once in every 300 nucleotides on average, which means there are roughly 10 million SNPs in any typical human genome. They can act as biological (diagnostic) markers.
Source:
PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1153 (https://doi.org/10.1515/pac-2016-1120)