06416 IUPAC Gold Book - toxicokinetics 10.1351/goldbook.T06416 T06416 current 1 Process of the uptake of potentially toxic substances by the body, the biotransformation they undergo, the distribution of the substances and their metabolites in the tissues, and the elimination of the substances and their metabolites from the body. Both the amounts and the concentrations of the substances and their metabolites are studied. The term has essentially the same meaning as pharmacokinetics, but the latter term should be restricted to the study of pharmaceutical substances. biotransformation https://goldbook.iupac.org//terms/view/B00667 elimination https://goldbook.iupac.org//terms/view/E02038 pharmacokinetics https://goldbook.iupac.org//terms/view/PT06835 uptake https://goldbook.iupac.org//terms/view/UT06806 PAC, 1993, 65, 2003. 'Glossary for chemists of terms used in toxicology (IUPAC Recommendations 1993)' on page 2108 (https://doi.org/10.1351/pac199365092003) https://goldbook.iupac.org/terms/view/T06416/html https://goldbook.iupac.org/terms/view/T06416/json https://goldbook.iupac.org/terms/view/T06416/plain Citation: 'toxicokinetics' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.T06416 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-06-28T09:12:00+00:00