Structure-property correlations (SPC) refer to all statistical mathematical methods used to correlate any molecular property (intrinsic, chemical or biological) to any other property, using statistical regression or pattern recognition techniques.
Source:
PAC, 1997, 69, 1137. 'Glossary of terms used in computational drug design (IUPAC Recommendations 1997)' on page 1150 (https://doi.org/10.1351/pac199769051137)