structure-based design

in drug design
https://doi.org/10.1351/goldbook.ST06981
Structure-based design is a design strategy for new chemical entities based on the three-dimensional (3D) structure of the target obtained by X-ray or nuclear magnetic @R05326@ (NMR) studies, or from protein homology models.
Source:
PAC, 1997, 69, 1137. (Glossary of terms used in computational drug design (IUPAC Recommendations 1997)) on page 1150 [Terms] [Paper]
Citation: 'structure-based design' in IUPAC Compendium of Chemical Terminology, 3rd ed. International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. https://doi.org/10.1351/goldbook.ST06981 RIS BibTex EndNote
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Last revised: February 24, 2014