Title: molar-mass exclusion limit
Long Title: IUPAC Gold Book - molar-mass exclusion limit
DOI: 10.1351/goldbook.M03978
Status: current

Definition
The maximum value of the molar mass or molecular weight of molecules or particles, in a specific polymer solvent system, that can enter into the pores of the porous non-adsorbing material used in size-exclusion chromatography. For particles with molar mass or molecular weight larger than the exclusion limit the separation effect of the size-exclusion chromatography vanishes.

Related Terms
- exclusion chromatography: https://goldbook.iupac.org//terms/view/E02261
- molecular weight: https://goldbook.iupac.org//terms/view/M04000
- polymer solvent: https://goldbook.iupac.org//terms/view/PT07189

Source
- Purple Book, 1st ed., p. 69 (http://old.iupac.org/publications/books/author/metanomski.html)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/M03978/html
- json: https://goldbook.iupac.org/terms/view/M03978/json
- xml: https://goldbook.iupac.org/terms/view/M03978/xml

Citation: Citation: 'molar-mass exclusion limit' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.M03978
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Accessed: 2026-06-20T08:34:06+00:00