Title: matrix effect
Long Title: IUPAC Gold Book - matrix effect
DOI: 10.1351/goldbook.M03759
Status: current

Definitions
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Definition (1)
The combined effect of all components of the sample other than the analyte on the measurement of the quantity. If a specific component can be identified as causing an effect then this is referred to as interference.

Related Term
- matrix: https://goldbook.iupac.org//terms/view/M03758

Source
- PAC, 1989, 61, 1657. 'Nomenclature for automated and mechanised analysis (Recommendations 1989)' on page 1660 (https://doi.org/10.1351/pac198961091657)

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Definition (2)
Effects which cause changes in Auger-electron, photoelectron, secondary ion yield, or scattered ion intensity, the energy or shape of the signal of an element in any environment as compared to these quantities in a pure element. (a) Chemical matrix effects: changes in the chemical composition of the solid which affect the signals as described above. (b) Physical matrix effects: topographical and/or crystalline properties which affect the signal as described above.

Source
- PAC, 1979, 51, 2243. 'General aspects of trace analytical methods—IV. Recommendations for nomenclature, standard procedures and reporting of experimental data for surface analysis techniques' on page 2247 (https://doi.org/10.1351/pac197951112243)

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Other Outputs
- html: https://goldbook.iupac.org/terms/view/M03759/html
- json: https://goldbook.iupac.org/terms/view/M03759/json
- xml: https://goldbook.iupac.org/terms/view/M03759/xml

Citation: Citation: 'matrix effect' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.M03759
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Accessed: 2026-04-27T16:01:13+00:00