Title: hydrophobicity
Long Title: IUPAC Gold Book - hydrophobicity
DOI: 10.1351/goldbook.HT06964
Status: current

Definition
Hydrophobicity is the association of non-polar groups or molecules in an aqueous environment which arises from the tendency of water to exclude non-polar molecules.

Related Term
- association: https://goldbook.iupac.org//terms/view/A00472

Source
- PAC, 1997, 69, 1137. 'Glossary of terms used in computational drug design (IUPAC Recommendations 1997)' on page 1145 (https://doi.org/10.1351/pac199769051137)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/HT06964/html
- json: https://goldbook.iupac.org/terms/view/HT06964/json
- xml: https://goldbook.iupac.org/terms/view/HT06964/xml

Citation: Citation: 'hydrophobicity' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.HT06964
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Accessed: 2026-05-18T09:21:08+00:00