Title: hydrophilicity Long Title: IUPAC Gold Book - hydrophilicity DOI: 10.1351/goldbook.HT06963 Status: current Definition Hydrophilicity is the tendency of a molecule to be solvated by water. Source - PAC, 1997, 69, 1137. 'Glossary of terms used in computational drug design (IUPAC Recommendations 1997)' on page 1145 (https://doi.org/10.1351/pac199769051137) Other Outputs - html: https://goldbook.iupac.org/terms/view/HT06963/html - json: https://goldbook.iupac.org/terms/view/HT06963/json - xml: https://goldbook.iupac.org/terms/view/HT06963/xml Citation: Citation: 'hydrophilicity' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.HT06963 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. Accessed: 2026-04-18T17:23:46+00:00