Title: Hansch analysis
Long Title: IUPAC Gold Book - Hansch analysis
DOI: 10.1351/goldbook.HT06962
Status: current

Definition
Hansch analysis is the investigation of the quantitative relationship between the biological activity of a series of compounds and their physicochemical substituent or global parameters representing hydrophobic, electronic, steric and other effects using multiple regression correlation methodology.

Source
- PAC, 1997, 69, 1137. 'Glossary of terms used in computational drug design (IUPAC Recommendations 1997)' on page 1144 (https://doi.org/10.1351/pac199769051137)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/HT06962/html
- json: https://goldbook.iupac.org/terms/view/HT06962/json
- xml: https://goldbook.iupac.org/terms/view/HT06962/xml

Citation: Citation: 'Hansch analysis' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.HT06962
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Accessed: 2026-04-18T17:44:38+00:00