Atoms or groups of a molecule which are related by an
n-fold rotation axis (
n = 2, 3, etc.) are called homotopic. For example, chiral tartaric acid (C2 axis), chloroform (C3 axis) and cyclohexaamylose (α-cyclodextrin, C6 axis) have respectively two homotopic carboxyl groups, three homotopic chlorine atoms and six homotopic
d-glucose residues.
See: prochirality
Source:
PAC, 1996, 68, 2193. 'Basic terminology of stereochemistry (IUPAC Recommendations 1996)' on page 2210 (https://doi.org/10.1351/pac199668122193)