comparative molecular field analysis (CoMFA)

https://doi.org/10.1351/goldbook.CT06951
Comparative Molecular Field Analysis (CoMFA) is a 3D-QSAR method that uses statistical correlation techniques for the analysis of the quantitative relationship between the biological activity of a set of compounds with a special alignment, and their three-dimensional electronic and steric properties. Other properties, such as @HT06964@ and H-bonding, can also be incorporated into the analysis.
Source:
PAC, 1997, 69, 1137. (Glossary of terms used in computational drug design (IUPAC Recommendations 1997)) on page 1140 [Terms] [Paper]
Citation: 'comparative molecular field analysis' in IUPAC Compendium of Chemical Terminology, 3rd ed. International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. https://doi.org/10.1351/goldbook.CT06951 RIS BibTex EndNote
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Last revised: February 24, 2014