Title: allosteric enzymes
Long Title: IUPAC Gold Book - allosteric enzymes
DOI: 10.1351/goldbook.A00240
Status: current

Definition
Enzymes which contain regions to which small, regulatory molecules (cf. effector) may bind in addition to and separate from substrate binding sites. On binding the effector, the catalytic activity of the enzyme towards the substrate may be enhanced, in which case the effector is an activator, or reduced, in which case it is an inhibitor.

Related Terms
- Enzymes: https://goldbook.iupac.org//terms/view/E02159
- activator: https://goldbook.iupac.org//terms/view/A00104
- effector: https://goldbook.iupac.org//terms/view/E01901
- inhibitor: https://goldbook.iupac.org//terms/view/I03035
- substrate: https://goldbook.iupac.org//terms/view/S06083

Source
- PAC, 1992, 64, 143. 'Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)' on page 146 (https://doi.org/10.1351/pac199264010143)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/A00240/html
- json: https://goldbook.iupac.org/terms/view/A00240/json
- xml: https://goldbook.iupac.org/terms/view/A00240/xml

Citation: Citation: 'allosteric enzymes' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.A00240
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Accessed: 2026-05-09T10:09:47+00:00