Title: irreversible alteration
Long Title: IUPAC Gold Book - irreversible alteration
DOI: 10.1351/goldbook.15835
Status: current

Definition
Change from normal structure or function that persists or progresses after cessation of exposure of the organism.

Source
- PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1247 (https://doi.org/10.1351/pac200779071153)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/15835/html
- json: https://goldbook.iupac.org/terms/view/15835/json
- xml: https://goldbook.iupac.org/terms/view/15835/xml

Citation: Citation: 'irreversible alteration' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15835
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-08-05T04:16:56+00:00