Title: dependence
Long Title: IUPAC Gold Book - dependence
DOI: 10.1351/goldbook.15633
Status: current

Definition
A psychic craving for a drug or other substance that may or may not be accompanied by a physical dependency.
Reliance on a drug or other substance to maintain health.

Related Term
- health: https://goldbook.iupac.org//terms/view/15757

Source
- PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1204 (https://doi.org/10.1351/pac200779071153)

Other Outputs
- html: https://goldbook.iupac.org/terms/view/15633/html
- json: https://goldbook.iupac.org/terms/view/15633/json
- xml: https://goldbook.iupac.org/terms/view/15633/xml

Citation: Citation: 'dependence' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15633
License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.
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Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.
Accessed: 2026-06-28T15:03:57+00:00