Title: cumulative median lethal dose Long Title: IUPAC Gold Book - cumulative median lethal dose DOI: 10.1351/goldbook.15618 Status: current Definition Estimate of the total administered amount of a substance that is associated with the death of half a population of animals when the substance is administered repeatedly in doses which are generally fractions of the median lethal dose. Source - PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1200 (https://doi.org/10.1351/pac200779071153) Other Outputs - html: https://goldbook.iupac.org/terms/view/15618/html - json: https://goldbook.iupac.org/terms/view/15618/json - xml: https://goldbook.iupac.org/terms/view/15618/xml Citation: Citation: 'cumulative median lethal dose' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15618 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. Accessed: 2026-04-17T23:04:05+00:00