15424 IUPAC Gold Book - transamidation 10.1351/goldbook.15424 15424 current synonym: amide interchange 1 Interchange reaction involving amide groups. Transamidations commonly occur during polycondensations to form polyamides. The reactions of an amide group with an amine group to give a new amide group plus a new amine group (aminolysis), of an amide group with a carboxylic acid group to give a new amide group plus a new carboxylic acid group (acidolysis), and of an amide group with another amide group to interchange substituents are all examples of transamidation. The reactions of an amide group with an amine group to give a new amide group plus a new amine group (aminolysis), of an amide group with a carboxylic acid group to give a new amide group plus a new carboxylic acid group (acidolysis), and of an amide group with another amide group to interchange substituents are all examples of transamidation. PAC, 2008, 80, 2163. 'Glossary of terms related to kinetics, thermodynamics, and mechanisms of polymerization (IUPAC Recommendations 2008)' on page 2185 (https://doi.org/10.1351/pac200880102163) https://goldbook.iupac.org/terms/view/15424/html https://goldbook.iupac.org/terms/view/15424/json https://goldbook.iupac.org/terms/view/15424/plain Citation: 'transamidation' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15424 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-04-18T06:51:10+00:00