15239 IUPAC Gold Book - sustained release 10.1351/goldbook.15239 15239 current synonyms: extended release, gradual release, long acting, prolonged action, slow release 1 Dosage form designed to release the drug contained therein at a continuous and controlled rate for a longer period of time that can normally be achieved with its conventional, nonsustained counterpart. Per-oral administration of a single dose of a sustained-release product increases the duration of therapeutic action of the drug, beyond that achieved normally with a single dose of the corresponding non-sustained conventional counterpart. Sustained-release injectables are also available. Other terms used to describe the same concept include: "controlled release", "extended release", "long-acting", "gradual release", "modified release", "prolonged action", and "slow release". Dosage form https://goldbook.iupac.org//terms/view/15175 PAC, 2009, 81, 971. 'Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009)' on page 997 (https://doi.org/10.1351/PAC-REC-04-10-14) https://goldbook.iupac.org/terms/view/15239/html https://goldbook.iupac.org/terms/view/15239/json https://goldbook.iupac.org/terms/view/15239/plain Citation: 'sustained release' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15239 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-05-31T09:56:11+00:00