15207 IUPAC Gold Book - matrix formulation 10.1351/goldbook.15207 15207 current 1 Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release. Matrices can be monolithic or heterogeneous, dissolved or dispersed, or both. This term also applies to a matrix made of hydrophilic substances, which, in contact with water, form a gel of high viscosity. Matrix tablet. https://goldbook.iupac.org//terms/view/1 embedding https://goldbook.iupac.org//terms/view/15183 extended release https://goldbook.iupac.org//terms/view/15239 PAC, 2009, 81, 971. 'Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009)' on page 990 (https://doi.org/10.1351/PAC-REC-04-10-14) https://goldbook.iupac.org/terms/view/15207/html https://goldbook.iupac.org/terms/view/15207/json https://goldbook.iupac.org/terms/view/15207/plain Citation: 'matrix formulation' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15207 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-05-31T09:11:14+00:00