<?xml version="1.0" encoding="UTF-8"?>
<term>
  <id>15166</id>
  <title>crystalline</title>
  <longtitle>IUPAC Gold Book - crystalline</longtitle>
  <doi>10.1351/goldbook.15166</doi>
  <code>15166</code>
  <status>current</status>
  <definitions>
    <item>
      <id>1</id>
      <text>Term that describes a solid of regular shape and the presence of three-dimensional order on the level of atomic dimensions, for a given molecule.</text>
      <notes>
        <item>Crystallinity may be detected by diffraction techniques, heat-of-fusion measurements, etc.</item>
        <item>Crystalline forms are often preferred, over amorphous forms, in pharmaceutical dosage forms, due to uniformity, reproducibility, and sometimes lack of hygroscopicity.</item>
      </notes>
      <links>
        <item>
          <term>dosage forms</term>
          <url>https://goldbook.iupac.org//terms/view/15175</url>
        </item>
      </links>
      <sources>
        <item>PAC, 2009, 81, 971. 'Glossary of terms related to pharmaceutics (IUPAC Recommendations 2009)' on page 981 (https://doi.org/10.1351/PAC-REC-04-10-14)</item>
      </sources>
    </item>
  </definitions>
  <altoutputs>
    <html>https://goldbook.iupac.org/terms/view/15166/html</html>
    <json>https://goldbook.iupac.org/terms/view/15166/json</json>
    <plain>https://goldbook.iupac.org/terms/view/15166/plain</plain>
  </altoutputs>
  <citation>Citation: 'crystalline' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15166</citation>
  <license>The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms.</license>
  <collection>If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .</collection>
  <disclaimer>The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.</disclaimer>
  <accessed>2026-04-17T21:33:06+00:00</accessed>
</term>
