Title: top-down ecotoxicological study Long Title: IUPAC Gold Book - top-down ecotoxicological study DOI: 10.1351/goldbook.15098 Status: current Definition Approach to investigating ecotoxicological effects that starts with a determination of the presence and nature of any adverse effects via responses at community and ecosystem levels of organization rather than the suborganismal levels of organization. Related Terms - bottom-up ecotoxicological study: https://goldbook.iupac.org//terms/view/14509 - community: https://goldbook.iupac.org//terms/view/14531 - ecosystem: https://goldbook.iupac.org//terms/view/14619 Source - PAC, 2009, 81, 829. 'Glossary of terms used in ecotoxicology (IUPAC Recommendations 2009)' on page 956 (https://doi.org/10.1351/PAC-REC-08-07-09) Other Outputs - html: https://goldbook.iupac.org/terms/view/15098/html - json: https://goldbook.iupac.org/terms/view/15098/json - xml: https://goldbook.iupac.org/terms/view/15098/xml Citation: Citation: 'top-down ecotoxicological study' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15098 License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. Collection: If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . Disclaimer: The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. Accessed: 2026-06-20T05:24:42+00:00