15095 IUPAC Gold Book - tiered testing 10.1351/goldbook.15095 15095 current 1 Structured approach to assessment of the fate and effects of substances, where a tier of relatively simple tests is used initially to select substances of concern and to define their toxicity. If the information from these tests is inadequate for regulatory decisions, further more complex tests (higher tier tests) may be required. For example, under a tiered structure, testing might progress from acute studies to chronic laboratory studies to field studies. PAC, 2009, 81, 829. 'Glossary of terms used in ecotoxicology (IUPAC Recommendations 2009)' on page 955 (https://doi.org/10.1351/PAC-REC-08-07-09) https://goldbook.iupac.org/terms/view/15095/html https://goldbook.iupac.org/terms/view/15095/json https://goldbook.iupac.org/terms/view/15095/plain Citation: 'tiered testing' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15095 The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https://creativecommons.org/licenses/by-sa/4.0/) for individual terms. If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org . The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using. 2026-04-21T15:08:12+00:00