{"term":{"id":"14196","title":"surface plasmon resonance assay","longtitle":"IUPAC Gold Book - surface plasmon resonance assay","doi":"10.1351\/goldbook.14196","code":"14196","status":"current","initialism":"<em>initialism<\/em>: SPR","synonym":"<em>synonym<\/em>: SPR Assay","definitions":[{"id":1,"text":"Assay in which the binding of a ligand to a target immobilized on the gold surface of a chip is detected by changes in the angle of the light reflected from the surface.","notes":{"1":"This assay type is not usually used for high-throughput screening but has been expanded to multiple simultaneous detection channels and has improved sensitivity to detect low-molecular-weight binding molecules."},"sources":["PAC, 2011, 83, 1129. 'Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)' on page 1155 (https:\/\/doi.org\/10.1351\/PAC-REC-09-05-03)"]}],"altoutputs":{"html":"https:\/\/goldbook.iupac.org\/terms\/view\/14196\/html","xml":"https:\/\/goldbook.iupac.org\/terms\/view\/14196\/xml","plain":"https:\/\/goldbook.iupac.org\/terms\/view\/14196\/plain"},"citation":"Citation: 'surface plasmon resonance assay' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351\/goldbook.14196","license":"The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International (https:\/\/creativecommons.org\/licenses\/by-sa\/4.0\/) for individual terms.","collection":"If you are interested in licensing the Gold Book for commercial use, please contact the IUPAC Executive Director at executivedirector@iupac.org .","disclaimer":"The International Union of Pure and Applied Chemistry (IUPAC) is continuously reviewing and, where needed, updating terms in the Compendium of Chemical Terminology (the IUPAC Gold Book). Users of these terms are encouraged to include the version of a term with its use and to check regularly for updates to term definitions that you are using.","accessed":"2026-04-17T23:37:44+00:00"}}