label-free assay

https://doi.org/10.1351/goldbook.14153
Assay in which there is no requirement to modify one of the interacting components in order to facilitate signal detection.
Note: Used to monitor macromolecule/macromolecule or small-molecule/macromolecule binding, as well as cell adhesion or cell signaling.
Examples: Assays in which calorimetry, mass spectrometry, or nuclear magnetic resonance provides the signal.
Source:
PAC, 2011, 83, 1129. (Glossary of terms used in biomolecular screening (IUPAC Recommendations 2011)) on page 1146 [Terms] [Paper]
Citation: 'label-free assay' in IUPAC Compendium of Chemical Terminology, 5th ed. International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. https://doi.org/10.1351/goldbook.14153 RIS BibTex EndNote
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