https://doi.org/10.1351/goldbook.14117
Compound that reduces or eliminates the conductance of an ion channel by impeding the movement of ions through that channel.
Note: Dihydropyridine antagonists such as nifedipine, which also block the conductance of some L-type calcium channels, are not classified as channel blockers since their action is to inhibit channel gating.
Example: Verapamil, which blocks the conductance of some L-type calcium channels.